Course objectives:
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| Development, characterization, methods and testing in experimental biology. |
Requirements on student
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| 80% fruitfulness on written exam |
Content
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| Introduction into cancer cell biology, Genomic approaches in experimental biology, Gene therapy, Protein engineering, Phage display, Protein preparation and purification, Development, characterization and utilization of antibodies, Models in application research, Human biological material in research, Predictive and prognostic pathology, Development, characterization and testing of the drugs, Utilization of viruses in experimental biology. |
Activities
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Guarantors and lecturers
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- Guarantors: RNDr. Bořivoj Vojtěšek, DrSc.,
- Lecturer: Mgr. Pavel Bouchal, Ph.D., prof. Ing. Lenka Hernychová, Ph.D., Mgr. Roman Hrstka, Ph.D., MUDr. Petr Müller, Ph.D., MUDr. Rudolf Nenutil, CSc., RNDr. Bořivoj Vojtěšek, DrSc.,
- Tutorial lecturer: Mgr. Pavel Bouchal, Ph.D., Mgr. Michal Ďurech, Mgr. Roman Hrstka, Ph.D., MUDr. Petr Müller, Ph.D., MUDr. Rudolf Nenutil, CSc., Mgr. Filip Trčka, RNDr. Bořivoj Vojtěšek, DrSc.,
- Seminar lecturer: Mgr. Roman Hrstka, Ph.D., RNDr. Bořivoj Vojtěšek, DrSc.,
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Literature
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- Recommended: Robert A. Antibody Phage Display: Methods and Protocols. A product of Humana Press,. 2009. ISBN 978-1-60327-301-5.
- Recommended: Hammers C., M., Stanley J., R.. Antibody Phage Display: Technique and Applications. Journal of Investigative Dermatology, 2014.
- Recommended: Douglas Hanahan and Robert A. Weinberg. Hallmarks of Cancer: The Next Generation. Cell 144, 2011.
- Recommended: Krejsek, J. a kol. Klinická imunologie. Nucleus HK, 2004.
- Recommended: Cassimeris L. et al. Lewin´s cells.. Sudbury: Jones and Bartlett Publishers, 2011.
- Recommended: Alberts, B. a kol. Molecular Biology of the Cell, 4th ed.. Garland Science, New York, 2002. ISBN 0815340729.
- Recommended: Slabý O, et al. Molekulární medicína.. Praha Galén 2014, 2014. ISBN 978-80-7492-121-6.
- Recommended: Klinická onkologie 2014 Supplementum. Postupy a metody v aplikoané molekulární onkologii?. 2014.
- Recommended: Robert A. Weinberg. The Biology of Cancer. Second Edition,. 2013. ISBN 978-08153422.
- Recommended: Harlow, E., Lane, D. Using antibodies. Cold Spring Harbor, New York, 1999.
- On-line library catalogues
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Time requirements
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Activities
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Time requirements for activity [h] |
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Homework for Teaching
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12 |
| Preparation for the Exam |
30
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| Total |
42
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Prerequisites – other information about course preconditions
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| – |
Competences acquired
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| Student should be able to (after attending the course): Introduction into cancer cell biology, Genomic approaches in experimental biology, Gene therapy, Protein engineering, Phage display, Protein preparation and purification, Development, characterization and utilization of antibodies, Models in application research, Human biological material in research, Predictive and prognostic pathology, Development, characterization and testing of the drugs, Utilization of viruses in experimental biology. |
Teaching methods
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Assessment methods
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Laboratory of Growth Regulators
Palacký University Olomouc